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Poster Session

Magnetic particle mapping using magnetoelectric sensors as an imaging modality

Tuesday (18.06.2019)
20:17 - 20:18

Magnetic nanoparticles have been investigated extensively for diagnostics and therapy in medical life science. Elaborate but also very expensive methods such as magnetic resonance imaging (MRI), magnetic particle imaging (MPI), and magnetorelaxometry imaging (MRX) were developed. Here we propose a novel technique, magnetic particle mapping (MPM), that uses resonant magnetoelectric sensors for the detection of magnetic nanoparticles. A simple and straightforward procedure for setup and measurement enables the detection of higher harmonic excitations of magnetic nanoparticle ensembles. We demonstrate the feasibility of such an approach by building a measurement system particularly suited to exploit the sensor’s inherent properties. We measure the magnetic response from 2D magnetic nanoparticle distributions and reconstruct the distribution by solving the inverse problem. Furthermore, biological samples with magnetically labeled cells were measured and reconstructions of the cell distributions were compared with the original distribution. The results suggest that our method is very promising technique for magnetic nanoparticle imaging in life science and other fields.

Speaker:
Ron-Marco Friedrich
Kiel University
Additional Authors:
  • Dr. Sebastian Zabel
    Kiel University
  • Dr. Andreas Galka
    Kiel University
  • Nils Lukat
    Kiel University
  • Dr. Jan-Martin Wagner
    Kiel University
  • Dr. Christine Kirchhof
    Kiel University
  • Prof. Dr. Eckhard Quandt
    Kiel University
  • Prof. Dr. Jeffrey McCord
    Kiel University
  • Prof. Dr. Christine Selhuber-Unkel
    Kiel University
  • Prof. Dr. Michael Siniatchkin
    Kiel University
  • Prof. Dr. Franz Faupel
    Kiel University